Starikov, V. V.Starikova, S. L.Mamalis, A. G.Lavrynenko, S. N.2020-01-202020-01-202016Features of medical implant passivation using anodic oxide films / V. V. Starikov [et al.] // Journal of Biological Physics and Chemistry. – 2016. – Vol. 16, No. 2. – P. 90-94.https://repository.kpi.kharkov.ua/handle/KhPI-Press/43814The passivation ability of metals from groups IV and V of the Periodic Table is considered. Anodic treatment is able to neutralize the increase of metal hardening when comminuting grains to nanometre sizes. The deposition of metal oxide film coatings on a cobalt–chromium alloy surface results in substantial passivation of its surface and prevents cobalt and chromium accumulation in bone tissues. The decrease of surface activity of titanium implants can be achieved both by cleaning the surface during vacuum annealing before oxidation and by the increase of the anodic oxide film thickness, which limits mass and charge transfer through the implant surface. Recommended titanium implant treatment regimens are vacuum annealing at 650 °C and anodic oxidation to attain an oxide thickness less or equal to 300 nm.enanodic oxidecoatingelectrode potentialimplantpassivationtitaniumArticledoi.org/10.4024/08ST16A.jbpc.16.02