Synthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic application

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dc.contributor.authorYanovska, А.en
dc.contributor.authorKuznetsov, V.en
dc.contributor.authorStanislavov, A.en
dc.contributor.authorHusak, Е.en
dc.contributor.authorPogorielov, М.en
dc.contributor.authorStarikov, V.en
dc.contributor.authorBolshanina, S.en
dc.contributor.authorDanilchenko, S.en
dc.date.accessioned2020-01-17T09:42:25Z
dc.date.available2020-01-17T09:42:25Z
dc.date.issued2016
dc.description.abstractThe composite materials based on hydroxyapatite (HA) and gelatine (Gel) with addition of silver and zirconium oxide were obtained. The study investigates a combination of low powered ultrasonic irradiation and low concentration of gelatine in the co-precipitation synthesis. These composites have different weight ratios of organic/inorganic components and may be synthesized in two ways: simple mixing and co-precipitation. Both of which were compared. The estimation of porosity, in vivo testing, surface morphology and phase composition as well as the IR-analysis were provided. Hydroxyapatite was the main crystalline phase in obtained composites. While around powdered HA-Gel composite the connective tissue capsule is formed without bone tissue formation, HA-Gel-Ag porous composite implantation leads to formation of new bone tissue and activation of cell proliferation. Addition of silver ions into composite material allows decreasing inflammation on the first stage of implantation and has positive effect on bone tissue formation. Some of the obtained composite materials containing silver or ZrO2 are biocompatible. bio-resorbable and osteoconductive with high level of porosity (75e85%).ru
dc.identifier.citationSynthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic application / А. Yanovska [et al.] // Materials Chemistry and Physics. – 2016. – Vol. 183. – P. 93-100.en
dc.identifier.urihttps://repository.kpi.kharkov.ua/handle/KhPI-Press/43779
dc.language.isoen
dc.publisherElsevieren
dc.subjectbiomaterialsen
dc.subjectchemical synthesisen
dc.subjectultrasonic techniquesen
dc.subjectprecipitationen
dc.subjectfourier transform infrared spectroscopyen
dc.titleSynthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic applicationen
dc.typeArticleen

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