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Документ Functional characteristics of the cardiovascular system of patients with ischemic heart disease with obesity(Wydawnictwo ALUNA, 2023) Zlatkina, Vira V.; Nemtsova, Valeriya D.; Fedak, Bogdan S.; Ponomaryov, Volodymyr I.; Zhelezniakova, Natalia M.; Mishchenko, Oleksandr M.; Horban, Dariia V.The aim: To determine the features of the functional characteristics of the cardiovascular system of patients with ischemic heart disease with obesity. Materials and methods: Examined 130 persons (mostly military personnel and persons who were in the zone of active hostilities): 65 patients (the main group, 62,67±8,93 years) with coronary heart disease and obesity and 45 people of the control group (virtually healthy people, randomized by age and sex, 58,76±14,6 years). Results: Coronary heart disease and obesity compared to healthy individuals probably the exceed all values of the functional state of the cardiovascular system: systolic blood pressure (152.72±14.61 and 119.03±7.94 mmHg; p<0.001); diastolic blood pressure (90.74±7.36 and 80.36±6.74 mmHg; p<0.001); end-diastolic volume (103.17±40.84 and 52.48±8.58 mm3; р<0.001); end-systolic volume (47.98±29.92 and 31.47±8.42 mm3; р=0.001); end-diastolic size (4.74±0.81 and 4.12 ± 0.27 cm; р<0.001); end-systolic size (3.34±0.76 and 3.17±0.59 cm; р=0.014). Conclusions: The identified functional disorders of the heart in the comorbid course of coronary heart disease and obesity can be used for early diagnosis of cardiovascular complications in such patients and for the development of adequate therapeutic schemes.Документ Determination of somatic, neurological and psycho-emotional manifestations of the acute and postcovid period in patients with a mild course of COVID-19 in wartime(Wydawnictwo ALUNA, 2023) Fedak, Bogdan S.; Ponomaryov, Volodymyr I.; Ponomaryova, Valeria V.; Kravchenko, Iryna M.; Morozova, Olga G.; Yaroshevskiy, Oleksandr A.; Mishchenko, Oleksandr M.The aim: To analyze the typical symptom complex at the stage of COVID-19 acute phase in the systemic relationship with somatic, psychosomatic, and neurological manifestations. Materials and methods: The collection of primary material was performed by clinical-anamnestic method, laboratory, and sociological examination of patients treated out patiently. Summarizing of the results was performed according to the analysis of 100 completed cases of COVID-19 in patients aged 35-45 years (50 men and 50 women) who had no concomitant chronic pathology, and patients did not receive any vaccine dose before the disease (acute COVID-19) and during the next follow-up period (6 months). Results: The data of the analysis allowed us to make a grounded conclusion about the syndromic heterogeneity of COVID 19 in a standardized patients group with a mild course. Conclusions: the highest number of symptoms in the postcovid period by frequency, polymorphism, and life quality impact was found in the group of patients with subjectively tolerate acute COVID-19 most easily. Patients whose acute episode meets the mild criteria have pronounced neurological and psychoemotional manifestations during the postcovid period.Документ Prevalence of anxiety and depression in patients after brain stroke(Державна наукова установа "Науково-практичний центр профілактичної та клінічної медицини" Державного управління справами, 2023) Mishchenko, Marina M.; Ognev, Victor A.; Mishchenko, Olexander M.; Ponomaryov, Volodymyr I.Introduction. WHO experts point to the urgency of the problem of cardiovascular diseases, among which the first places are occupied by cerebral strokes (CS). With CS there are significant changes in the socio-psychological activities of the patient and the personal psychological characteristics of the individual. Such changes provoke the development of certain psychological disorders, which are characterized by an oppressed state, a persistent depressive state, the development of anxieties and fears, obsessive fixation on the transferred disease and worries about one’s future, etc. That’s why, the study of psychological characteristics of patients after СS is a relevant problem of great importance, which determined the direction of our research.The aim: To investigate and analyze the prevalence of anxiety and depression in patients after CS.Materials and methods. Conducted a randomized controlled single- center prospective study case-control, which is based on the analysis of the results of psychological study of 300 patients after CS (main group) and 200 people of the control group for the period 2022-2023. The studied groups were randomized by age and gender. To study the psychological characteristics of patients after CS, we used two methods of diagnosing psychological conditions: the self-esteem scale of Spielberg Ch. D. and Khanin Yu.L. and the depression scale of Balashova T. I.Results. Probably (p<0.001) among the subjects of the main group compared to the control, a significantly higher frequency of occurrence of medium and moderate levels of reactive anxiety (RA), personal anxiety (PA) and levels of depression (LD) was determined, in contrast to low, which was more often detected among the persons control group. It was determined that the levels of RA, PA and depression were reliably significantly higher in the main group compared to the control group and characterized the presence of fairly significant moderate anxiety and mild depression of situational or neurotic origin.Conclusion. It has been proven probable (p<0.001) confirmation of the influence of an CS on the development of high levels of anxiety (both RA and PA) and depression.