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Документ Effects of semi-refined carrageenan (food additive E407a) on cell membranes of leukocytes assessed in vivo and in vitro(2021) Tkachenko, A. S.; Onishchenko, A.; Roshal, Alexander; Nakonechna, O.; Chumachenko, T.; Posokhov, Ye. O.No noticeable changes in the physico-chemical properties were observed in the lipid membranes of leukocytes in the region where the probes locate in response to oral intake of semi-refined carrageenan. Incubation of leukocytes with E407a solutions resulted in a decrease in polarity and proton-donor ability of leukocytes in the area of carbonyl groups of phospholipids and in the area of hydrocarbon chains of phospholipids near the polar region of the bilayer.Документ Semi-Refined Carrageenan Attenuates Lipopolysaccharide-Induced Reactive Oxygen Species Production in Peripheral Blood Mononuclear Cells and Cell Membrane Alterations in Leukocytes(2021) Posokhov, Ye. O.; Onishchenko, A.; Chumachenko, T.; Makieieva, N.; Kalashnyk-Vakulenko, Y.; Polikarpova, H.; Novikova, V.; Prokopyuk, V.; Nakonechna, O.; Chumachenko, D.; Tkachenko, V.; Meniailov, I.; Tkachenko, M.; Tkachenko, A. S.Expectedly, incubation with LPS induced ROS generation in PBMCs and decreased the lipid order of cell membranes in leukocytes. E407a alone was found to alter neither ROS production in PBMCs, nor membrane lipid order in leukocytes. Semi-refined carrageenan partially reduced LPS-mediated ROS overproduction in PBMCs and cell membrane alterations in leukocytes.Документ Automatic control of temperature and power conditions during rough grinding of slabs(Національний технічний університет "Харківський політехнічний інститут", 2021) Tihenko, V.; Lebedev, V. V.; Chumachenko, T.The production of high-quality rolled products (slabs), the formation of its surface phase-structural composition, texture, stress state during rough grinding depends on the temperature in the area of contact between the wheel and the slab. During processing, due to geometric errors of the rolled surface, as well as due to local changes in hardness, periodic fluctuations of the instantaneous depth of cut occur, which can be determined indirectly by controlling one of the technological parameters, for example, the power spent on grinding, with subsequent recalculation it to online temperature values. The grinding temperature is described as a control object in the form of an aperiodic link. Computer simulation has confirmed the efficiency of the system for maintaining the specified temperature of slab grinding under various operating conditions that simulate the situations of real production.