CYP2C19 gene polymorphism in children with drugs-resistant epilepsy in Ukraine

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dc.contributor.authorTantsura, Y.
dc.contributor.authorTantsura, L.
dc.contributor.authorPylypets, O.
dc.contributor.authorTretyakov, D.
dc.date.accessioned2024-06-24T11:31:34Z
dc.date.available2024-06-24T11:31:34Z
dc.date.issued2019
dc.description.abstractThe frequency with which drugs-resistant epilepsies occur is unchanged and reaches 30%. It is believed that isoenzymes of cytochrome P450 can significantly affect the metabolism, efficacy and safety of AEDs. The purpose of our study was to find out in children with drug-resistant epilepsy the frequency with which polymorphism of isoenzymes of cytochrome P450 - CYP2С19 occurs taking part in biotransformation of most AEDs.
dc.identifier.citationCYP2C19 gene polymorphism in children with drugs-resistant epilepsy in Ukraine [Electronic resource] / Tantsura Y., Tantsura L., Pylypets O., Tretyakov D. // Journal of Alzheimers Disease & Parkinsonism : [Parkinsons & Huntington Disease : 5th World Congress and Epilepsy & Treatment : 5th Intern. Conf., August 29-31, 2019. – Electronic text data. – Vienna, 2019. – Vol. 09. – P. 49. – Access mode: https://www.omicsonline.org/conference-proceedings/cyp2c19-gene-polymorphism-in-children-with-drugsresistant.pdf, free (date of the application 24.06.2024.).
dc.identifier.orcidhttps://orcid.org/0000-0003-4060-3159
dc.identifier.orcidhttps://orcid.org/0000-0002-7537-431X
dc.identifier.orcidhttps://orcid.org/0000-0002-3471-0145
dc.identifier.orcidhttps://orcid.org/0000-0002-1112-5752
dc.identifier.urihttps://repository.kpi.kharkov.ua/handle/KhPI-Press/78675
dc.language.isoen
dc.subjectdrugs-resistant epilepsies
dc.subjectgene polymorphism
dc.subjectallele variant CYP2C19*2
dc.subjectmetabolism
dc.subjectmedicine
dc.titleCYP2C19 gene polymorphism in children with drugs-resistant epilepsy in Ukraine
dc.typeArticle

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