Кафедра "Органічний синтез та фармацевтичні технології"

Постійне посилання колекціїhttps://repository.kpi.kharkov.ua/handle/KhPI-Press/7484

Офіційний сайт кафедри http://web.kpi.kharkov.ua/nanochem

Від січня 2022 року кафедра має назву "Органічний синтез та фармацевтичні технології", попередня назва – "Органічний синтез та нанотехнології" (НАКАЗ 31 ОД від 21.01.2022 року).

Найбільш істотну реорганізацію зазнала кафедра в 1929-1950 роках, коли відбувся поділ на ряд галузевих інститутів, і в їх числі був організований Харківський хіміко-технологічний інститут (ХХТІ). Кафедра технології органічних і фарбувальних речовин була розділена на 3 випускаючі кафедри: кафедра коксобензольного виробництва, кафедра технології органічних барвників і проміжних продуктів і кафедра технології жирів. Кафедра коксобензольного виробництва в 1933 році була перейменована в кафедру технології пірогенних процесів, в 1946 році – в кафедру хімічної технології палива, в 1959 році – в кафедру хімічної технології твердого палива. У 1975 році створено кафедру "Технологія органічних речовин" шляхом злиття кафедр хімічної технології твердого палива та технології органічних барвників і проміжних продуктів.

Кафедра входить до складу Навчально-наукового інституту хімічних технологій та інженерії Національного технічного університету "Харківський політехнічний інститут".

У складі науково-педагогічного колективу кафедри працюють: 2 доктора наук: 1 – фармацевтичних, 1 – біологічних; 7 кандидатів наук: 3 – технічних, 3 – фармацевтичних, 1 – хімічних; 1 співробітник має звання професора, 7 – доцента 1 – старшого наукового співробітника.

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Фільтри

2017 - 20203

Налаштування

ORCID: search.filters.orcid.https://orcid.org/ 0000-0003-4399-7907

Результати пошуку

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  • Ескіз
    Документ
    Analysis of the influence of technological parameters of the chlorogenic acid extraction process from sunflower meal on the degree of its extraction
    (Технологический Центр, 2020) Labeiko, Marina; Gladkiy, Fedir; Bochkarev, Sergiy; Mazaeva, Viktoria; Litvinenko, Olena; Ovsiannikova, Tetiana; Zhyrnova, Svitlana; Sytnik, Natalia
    The object of research is the efficiency of extraction of chlorogenic acid ‑ the natural antioxidant, depending on the conditions of its extraction from sunflower meal. The main problem of this issue is the fact that the extraction degree of the specified phenolic compound is influenced by many factors, such as the degree of grinding of the product, the type of raw material, the method of extraction, the nature of the solvent-extractant, the temperature and duration of the extraction process, the hydromodule in the system "raw – extractant" etc. The impact of each of these parameters requires careful consideration and appropriate research. This will determine the optimal values of the specified parameters of the extraction process and increase the efficiency of extraction of chlorogenic acid. In this work, the raw material for the production of chlorogenic acid is a meal made from sunflower seeds – a cheap second raw material of oil and fat production. Previous studies have found that a high-efficiency extractant of the specified antioxidant is a solution of ethyl alcohol with a concentration of 60 %, and the optimum temperature of the process of extracting chlorogenic acid from sunflower meal is the boiling point of the extractant. As a result of this study, the regularity of the influence on the extraction degree of chlorogenic acid of such technological parameters as the hydromodule in the system "meal – ethyl alcohol solution 60 %" (hereinafter referred to as "meal – extractant") and the duration of the extraction process were studied. Experiments to determine the dependence of the extraction degree of chlorogenic acid on the hydromodule in the system "meal – extractant" and the duration of extraction were carried out in accordance with the plan of the full factor experiment. Mathematical methods using the Microsoft Office Excel 2003 (USA) and Stat Soft Statistica v6.0 (USA) software packages have been applied for experiment planning and data processing. The dependence indicated in the paper is a quadratic function that predicts an increase in chlorogenic acid content during extraction, with an increase in the hydromodule in the "meal‑extractant" system from 1:5 to 1:10 and a decrease in the extraction time from 60 minutes up to 30 minutes. It is established that for the maximum possible increase in the extraction degree of chlorogenic acid from the meal of sunflower seeds, the optimal value of the hydromodule extraction ‑ 1:10, the duration of extraction ‑ 30 minutes. The obtained results allow to increase the extraction degree of chlorogenic acid from sunflower meal from 2.46 % to 5.58 %. This indicates the possibility of increasing the efficiency of extraction of antioxidant more than 2 times.
  • Ескіз
    Документ
    Research of influence of technological processing parameters of protein-fat base for supply of sportsmen on activity of protease inhibitors
    (Technology center, 2017) Bochkarev, Sergiy; Krichkovska, Lidiya; Petrova, Iryna; Petrov, Serhii; Varankina, Oleksandra; Belinska, Anna
    The object of research is the biological value of the protein-fat base for athletes, workers of heavy physical labor, military personnel, depending on the conditions of its preliminary processing. A technological audit, the purpose of which was to determine the change in the content of amino acids after enzymatic hydrolysis in samples of the protein-fat base, that had undergone pretreatment by microwave radiation, was conducted. The effectiveness of the protein-fat base pretreatment by microwave radiation was evaluated on the amount of α-amino nitrogen after enzymatic hydrolysis. Based on the analysis of the obtained data, the optimal conditions of the protein-fat base pretreatment were established: 250–350 seconds of microwave treatment time and its hydration to the 12–14 % of moisture content. Such processing will increase the biological value of the protein-fat base, namely, increase the degree of digestion and digestibility of proteins in the gastrointestinal tract.
  • Ескіз
    Документ
    Research of the oilseeds ratio on the oxidative stability of the protein-fat base for sportsmen
    (Technology center, 2017) Bochkarev, Sergiy; Matveeva, Tatiana; Krichkovska, Lidiya; Petrova, Iryna; Petrov, Serhii; Belinska, Anna
    The problem of improving physical performance and accelerating the course of recovery processes after physical exertion is one of the most pressing problems of medicine and sports. Nutrition is one of the main controlled factors that ensure the normal development of the body, health and quality of life. Nowadays the assortment of products is mainly expanded due to introduction of new technologies, application of new chemical compounds, development of genetic engineering. At the same time, daily food cannot provide the athlete's body with nutrients in the required amount. And, as a result, in recent years, to speed up regeneration, actively replenish spent plastic and energy resources, very often in sports use biologically active additives. One of the promising areas for improving the efficiency of athletes is the introduction in food rations qualitatively new food products that meet the needs of their body and at the same time have a long shelf life. The aim of this study is to evaluate the oxidation processes of the protein-fat basis, which can be used to organize the rational nutrition of athletes. The oxidative stability of the crushed sunflower seeds, sesame seeds, flax and mixtures was studied at various component ratios. It has been established that sesame seeds are the least susceptible to oxidation, and most of all – flax seeds. Among mixtures of seeds, the most prone to oxidation are mixtures that contain flax seeds and sunflower seeds. When adding sesame seeds to the mixture, the oxidative stability increases sharply. The optimal content (% by weight) of oil seeds in a protein-fat basis was calculated using the method of mathematical experiment planning in the software package "Statistica". The period of induction of oxidation of this mixture is 1.3–1.4 times higher than the induction period of sunflower seeds and 2.7–3.0 times higher than the induction period of flax seed. The use of such basis in food technologies, in particular the confectionery industry, opens up wide opportunities for expanding the range of specialized products for athletes.